More life, less itch— for your whole family

Because every moment matters

Say goodbye to skin distractions

Bug bites, rashes, and sunburns can strike at the worst times, turning your day into an itchy, painful distraction. You need relief that works fast—so you can get back to what matters.

PBZ OTC is the only topical itch relief cream trusted for ages 2 to 102, delivering powerful yet gentle soothing where you need it most.

Prescription-strength OTC

Fast relief,
no prescription

For years, the ingredient powering PBZ OTC was a trusted prescription oral antihistamine. But now—for the first time ever—you can get that same relief over the counter. Fast, targeted soothing for itching and discomfort from insect bites, poison ivy, and minor burns.

Worry-free

Steroid-free and safe to use alongside oral diphenhydramine.

Family-friendly

Gentle enough for toddlers, effective enough for adults.

All-in-one

Ditch the multiple creams for every bump, bug bite, or scrape.

Fast, targeted comfort

Relief is just a step away

Soothe minor skin irritations in seconds. PBZ OTC’s fast-absorbing formula delivers targeted relief exactly where you need it, so you can get back to feeling comfortable, confident, and in control. One quick application, and you’re on your way to take on the day.

1. Apply PBZ OTC

Gentle, fast absorbing cream provides targeted relief.

2. Feel the difference

Quickly soothes itch and pain from bites, scrapes, and burns.

3. Get back to what matters

Enjoy life without distraction and discomfort.

Taking oral allergy medications?

Get relief without second-guessing

PBZ OTC is the only topical antihistamine that works safely with oral allergy medications containing diphenhydramine—no risks, no overlap, just fast comfort when you need it.

Real stories, real comfort

Life’s too busy to let an itch get in the way

Don’t let itchy skin distract you from life’s best moments—whether it’s cheering at a ballgame, hiking with friends, or enjoying time with family, PBZ OTC gives you fast, effective relief.

This cream was effective in managing itch from a bug bite. I appreciate having a good working alternative to hydrocortisone cream, which I'm hesitant to use very often.

— Dan

No scent at all, and my whole family can use it! I used it for my daughter, who is 4 years old, with a sunburn, and it worked well. I put it in my family first aid kit, ready for a summer trip!

— Emily

My daughter stepped on a wasp. We put this on and she immediately calmed down. She didn't complain about the sting anymore after applying PBZ OTC.

— Mary

This came just in time for the summer season when we are exposed to plants & insects. Great value for all you get! I will definitely be throwing this in my purse while we are outdoors.

— Christine

A wonderful, non-greasy and quick absorbing cream that really does work. There is a light scent along with an almost cooling feel to this cream. Results take less than a minute!

— Carolyn

My husband either got into poison ivy or was bit by an insect and was itching fiercely. He put a little dab of this cream on and the itching stopped immediately! After two applications, the bump was gone!

— Nora

Consumers

Life without itch starts here

PBZ OTC is now available at Target. Get it today and enjoy worry-free comfort for the whole family!

Retailers

Bring an award-winning product to your shelves

Demand for safe, effective itch relief is on the rise—and PBZ OTC is leading the way. Join top retailers in offering the first new topical antihistamine in decades, backed by science and trusted by families.